CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Gc-globulin concentrations modify the effect of profibrogenic C5 haplotypes on serum activities of complement factor C5
DOI 10.1055/s-2006-950848
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Autor:innenO Gressner, U Meier, S Hillebrandt, HE Wasmuth, J Köhl, T Sauerbruch, AM Gressner, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Complement factor C5 is a quantitative trait gene that modifies liver fibrogenesis in mice. Haplotype-tagging single nucleotide polymorphisms (htSNPs) of the human C5 gene have been shown to be associated with higher total C5 serum levels and with advanced liver fibrosis in chronic hepatitis C virus infection. Our aim now was to investigate the role of group-specific component (Gc)-globulin as co-factor in reg…
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Zitierempfehlung
O Gressner, U Meier, S Hillebrandt, HE Wasmuth, J Köhl, T Sauerbruch, AM Gressner, F Lammert (2006) Gc-globulin concentrations modify the effect of profibrogenic C5 haplotypes on serum activities of complement factor C5. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950848
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