CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Hypoxia inducible factor 1α (HIF-1α) regulates the malignant progression of gastric cancer
DOI 10.1055/s-2006-950910
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Autor:innenN Rohwer, M Vieth, W Kemmner, PM Schlag, M Höcker, T Cramer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Hypoxia is a hallmark of solid tumor growth and a negative predictor of patient survival. Adaptation to hypoxia is mainly achieved by the transcription factor HIF-1α, which is upregulated in a diverse range of human and experimental tumors and their metastases. HIF-1α target genes have been implicated in the induction of invasion and metastasis. Gastric cancer represents the second largest cause of can…
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Zitierempfehlung
N Rohwer, M Vieth, W Kemmner, PM Schlag, M Höcker, T Cramer (2006) The Hypoxia inducible factor 1α (HIF-1α) regulates the malignant progression of gastric cancer. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-950910
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