CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Carbon monoxide, a natural product of HO enzymatic action, rescues mice from fulminant hepatitis
DOI 10.1055/s-2006-951165
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Autor:innenTY Tsui, HJ Schlitt
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Heme oxygenase (HO) enzymes cleave the pro-oxidant heme molecule into carbon monoxide (CO), ferrous iron, and biliverdin, which is subsequently converted to bilirubin. Among three identified isoforms of HO, HO-1 is inducible and widely expressed under stress conditions in parenchymal and non-parenchymal cells of liver. In this study, we showed that HO-1 was protective against fulminant hepatitis in a siRNA experimen…
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Zitierempfehlung
TY Tsui, HJ Schlitt (2006) Carbon monoxide, a natural product of HO enzymatic action, rescues mice from fulminant hepatitis. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2006-951165
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