CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
P16 Specific IFN-gamma Secreting T Cells in Tumor Infiltrating Populations of Cervical Intraepithelial Neoplasia (CIN) and Cervical Cancer
DOI 10.1055/s-2006-952490
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Autor:innenH von Keyserling, M Linnebacher, N Wentzensen, M von Knebel Doeberitz, A Schneider, AM Kaufmann
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Infection by human papillomavirus (HPV) is a necessary event in development of cervical cancer. More than 18 different so called high-risk (hr) HPV types cause immortalization of cervical epithelial cells. In response to the action of the viral oncogene E7 a regulatory feed back loop leads to upregulation of the cyclin-dependent kinase inhibitor p16INK4a. In turn, p16 INK4a is consistently over expressed in hr-HPV i…
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Zitierempfehlung
H von Keyserling, M Linnebacher, N Wentzensen, M von Knebel Doeberitz, A Schneider, AM Kaufmann (2006) P16 Specific IFN-gamma Secreting T Cells in Tumor Infiltrating Populations of Cervical Intraepithelial Neoplasia (CIN) and Cervical Cancer. Geburtshilfe und Frauenheilkunde (09). https://doi.org/10.1055/s-2006-952490
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