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More severe chronic phase experimental autoimmune encephalomyelitis with altered T-lymphocyte distribution and increased demyelinating lesions in CXCR3-deficient mice

M. Müller, S. Carter, P. Manders, M. Hofer, A. Dreykluft, E.B. Ringelstein, I.L. Campbell · Aktuelle Neurologie · Ausgabe 09/2006

DOI 10.1055/s-2006-952966

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Autor:innenM. Müller, S. Carter, P. Manders, M. Hofer, A. Dreykluft, E.B. Ringelstein, I.L. Campbell
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Chemokines and their receptors are intimately involved in the pathogenesis of inflammatory diseases of the CNS. The chemokine receptor CXCR3 is important for trafficking of activated T-cells and mediates the chemotactic properties of its ligands CXCL9, CXCL10 and CXCL11. Although these chemokines are highly expressed in MS and the corresponding animal model EAE, their role in CNS autoimmune diseases is not well defi…

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Zitierempfehlung

M. Müller, S. Carter, P. Manders, M. Hofer, A. Dreykluft, E.B. Ringelstein, I.L. Campbell (2006) More severe chronic phase experimental autoimmune encephalomyelitis with altered T-lymphocyte distribution and increased demyelinating lesions in CXCR3-deficient mice. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-952966

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