CareLit · DOI-Nachweis · Aktuelle Neurologie
New loci for restless legs syndrome map to chromosome 4q and 17p
DOI 10.1055/s-2006-952980
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ. Winkelmann, P. Lichtner, D. Kemlink, O. Polo, P. Montagna, B. Högl, K. Stiasny-Kolster, G. Hadjigeorgiou, B. Pütz, C. Trenkwalder, T.M. Strom, T. Meitinger, B. Müller-Myhsok
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: Three loci for RLS on chromosomes 12q, 14q and 9p (RLS1, RLS2 and RLS3) have been mapped, and evidence for further genetic locus heterogeneity has been shown. Methods: We conducted a genome-wide linkage analysis of a large RLS family of German origin. Results: Parametric two-point linkage analysis revealed a log odds (LOD) score of 2.3 and 2.1 and a multipoint LOD score of 3.08 and 2.78 on chromosome 4 an…
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Zitierempfehlung
J. Winkelmann, P. Lichtner, D. Kemlink, O. Polo, P. Montagna, B. Högl, K. Stiasny-Kolster, G. Hadjigeorgiou, B. Pütz, C. Trenkwalder, T.M. Strom, T. Meitinger, B. Müller-Myhsok (2006) New loci for restless legs syndrome map to chromosome 4q and 17p. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-952980
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