CareLit · DOI-Nachweis · Aktuelle Neurologie
Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis
DOI 10.1055/s-2006-952989
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Nachweis in CareLit
Autor:innenS. Petri, M. Kiaei, M. Damiano, A. Hiller, E. Wille, G. Manfredi, N.Y. Calingasan, H.H. Szeto, M.F. Beal
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Reactive oxygen species (ROS) play a major role in the pathogenesis of neurodegenerative diseases. They are important contributors to necrotic and apoptotic cell death. Structural and functional abnormalities of mitochondria resulting in the generation of ROS, aggregate formation and the release of proapoptotic factors are implicated in ALS pathogenesis. Results: In the present study we investigated a…
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Zitierempfehlung
S. Petri, M. Kiaei, M. Damiano, A. Hiller, E. Wille, G. Manfredi, N.Y. Calingasan, H.H. Szeto, M.F. Beal (2006) Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-952989
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