CareLit · DOI-Nachweis · Aktuelle Neurologie
COX-2 expression and CGRP release in primary trigeminal ganglion neurons – implications for the pathophysiology of migraine
DOI 10.1055/s-2006-953018
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL. Neeb, J. Hoffmann, C. Böhnke, S. Blumenau, U. Dirnagl, U. Reuter
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Trigeminal neurons are crucial for the pathophysiology of headache. In vivo, a host of stimuli leads to the release of neuropeptides e.g. calcitonine related peptide (CGRP). CGRP is known to play a crucial role in migraine pathophysiology and the transmission of pain. Serotonin receptor (5 HT1B/D) agonists, so called triptans, are able to cause significant pain relief in migraine attacks by blocking CGRP release. In…
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Zitierempfehlung
L. Neeb, J. Hoffmann, C. Böhnke, S. Blumenau, U. Dirnagl, U. Reuter (2006) COX-2 expression and CGRP release in primary trigeminal ganglion neurons – implications for the pathophysiology of migraine. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953018
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