CareLit · DOI-Nachweis · Aktuelle Neurologie
4-Aminopyridine restores neural integrator function in downbeat nystagmus
DOI 10.1055/s-2006-953052
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR. Kalla, S. Glasauer, U. Büttner, T. Brandt, M. Strupp
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Downbeat nystagmus (DBN), the most common form of acquired fixation nystagmus is often caused by cerebellar lesions. The precise pathomechanism is not yet known, but may be due to a deficiency of inhibitory floccular purkinje cell (PC) output. The potassium-channel blocker 4-aminopyridine (4-AP) has been shown to increase the excitability of cerebellar PCs. To test whether 4-AP is suited as treatment option for DBN,…
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Zitierempfehlung
R. Kalla, S. Glasauer, U. Büttner, T. Brandt, M. Strupp (2006) 4-Aminopyridine restores neural integrator function in downbeat nystagmus. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953052
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