CareLit · DOI-Nachweis · Aktuelle Neurologie
Characterisation of a conditional mouse-model of Parkinson's disease
DOI 10.1055/s-2006-953108
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Autor:innenS. Nuber, E. Petrasch-Parwez, T. Schmidt, H. Habbes, M. Löbbecke-Schumacher, P. Teismann, J.B. Schulz, M. Neumann, M. Fendt, B. Pichler, H. Nguyen, D. Berg, C. Holzmann, J. Boy, M. Kuhn, S. von Hörsten, I. Schmitt, A. Bornemann, F. Zimmermann, W. Kuhn, S.B. Prusiner, A. Servadio, K. Dietz, O. Rieß
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
alpha-Synuclein has been implicated in the pathophysiology of many neurodegenerative disorders, including Parkinson's disease (PD). In order to elucidate the role of this protein in the pathogenesis of PD, transgenic mice were created by using the tet-regulatable system driving the expression of human wildtype and mutated [A30P] alpha-synuclein in CNS neurons. Our studies demonstrate that the expression pattern depe…
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Zitierempfehlung
S. Nuber, E. Petrasch-Parwez, T. Schmidt, H. Habbes, M. Löbbecke-Schumacher, P. Teismann, J.B. Schulz, M. Neumann, M. Fendt, B. Pichler, H. Nguyen, D. Berg, C. Holzmann, J. Boy, M. Kuhn, S. von Hörsten, I. Schmitt, A. Bornemann, F. Zimmermann, W. Kuhn, S.B. P… (2006) Characterisation of a conditional mouse-model of Parkinson's disease. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953108
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