CareLit · DOI-Nachweis · Aktuelle Neurologie
Identification and characterisation of localisation signals in ataxin-3, the affected protein in spinocerebellar ataxia type 3
DOI 10.1055/s-2006-953113
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT. Schmidt, P.M.A. Antony, O. Rieß
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Spinocerebellar Ataxia Type 3 (SCA3), also known as Machado-Joseph disease (MJD), is an autosomal dominantly inherited neurodegenerative disorder caused by the expansion of a CAG stretch in the MJD1 gene encoding a polyglutamine repeat in the respective ataxin-3 protein. SCA3 therefore belongs to the group of the so called polyglutamine diseases. Ataxin-3 is mainly localized in the cytoplasm. However, one hallmark o…
Zitieren
Zitierempfehlung
T. Schmidt, P.M.A. Antony, O. Rieß (2006) Identification and characterisation of localisation signals in ataxin-3, the affected protein in spinocerebellar ataxia type 3. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953113
Mit CareLit weiterarbeiten