CareLit · DOI-Nachweis · Aktuelle Neurologie
Suppression of microglial inflammatory activity by myelin phagocytosis: role of reactive oxygen species generation via p47-PHOX
DOI 10.1055/s-2006-953214
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Nachweis in CareLit
Autor:innenY. Liu
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Multiple sclerosis (MS) is pathologically characterized by inflammatory demyelination and neuronal injury. Although phagocytosis of myelin debris by microglia and macrophages in acute MS lesion sites is well documented, its pathophysiological significance is unclear. Using real-time quantitative PCR, flow cytometry, ELISA and reactive oxygen species (ROS) measurement assays, we demonstrated that myelin phagocytosis…
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Zitierempfehlung
Y. Liu (2006) Suppression of microglial inflammatory activity by myelin phagocytosis: role of reactive oxygen species generation via p47-PHOX. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953214
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