CareLit · DOI-Nachweis · Aktuelle Neurologie
The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischaemia
DOI 10.1055/s-2006-953265
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE. Kilic, U. Kilic, Y. Wang, C.L. Bassetti, H.H. Marti, D.M. Hermann
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Based on its trophic influence on neurons and vascular cells, vascular endothelial growth factor (VEGF) is a promising candidate for stroke treatment. VEGF's survival-promoting effects are purchased at the expense of an increased blood brain barrier permeability, which potentially compromises tissue survival. The mechanisms via which VEGF protects the brain against ischemia remained unknown. Methods and result…
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Zitierempfehlung
E. Kilic, U. Kilic, Y. Wang, C.L. Bassetti, H.H. Marti, D.M. Hermann (2006) The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischaemia. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953265
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