CareLit · DOI-Nachweis · Aktuelle Neurologie
Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischaemia
DOI 10.1055/s-2006-953276
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Nachweis in CareLit
Autor:innenA. Spudich, E. Kilic, U. Kilic, K.M. Rentsch, H. Wunderli-Allenspach, C.L. Bassetti, D.M. Hermann
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Purpose and methods: The blood-brain barrier possesses transporters on its luminal surface, which carry back xenobiotics into the vasculature against concentration gradients. To define the role of one of them, multidrug resistance transporter (Mdr)-1, which is physiologically expressed in the brain and made responsible for pharmacoresistance in epilepsy, we subjected mice to middle cerebral artery occlusions. Result…
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Zitierempfehlung
A. Spudich, E. Kilic, U. Kilic, K.M. Rentsch, H. Wunderli-Allenspach, C.L. Bassetti, D.M. Hermann (2006) Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischaemia. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953276
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