CareLit · DOI-Nachweis · Aktuelle Neurologie
AMPA receptor mediated excitotoxicity in ALS: pathophysiology and neuropharmacology
DOI 10.1055/s-2006-953336
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK.G. Krampfl, F. Schlesinger, A. Cordes, L. Jin, S. Petri, J. Bufler, R. Dengler
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The term excitotoxicity was coined for the overstimulation of neurons via glutamate receptor channels. AMPA-type glutamate receptors (AMPA-R) are the most abundant excitatory transmitter receptors of the central nervous system. They play a major role in the cascade of cell damage in neurodegenerative diseases like amyotrophic lateral sclerosis. Neurons that are vulnerable to excitotoxicity express specific subtypes…
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Zitierempfehlung
K.G. Krampfl, F. Schlesinger, A. Cordes, L. Jin, S. Petri, J. Bufler, R. Dengler (2006) AMPA receptor mediated excitotoxicity in ALS: pathophysiology and neuropharmacology. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953336
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