CareLit · DOI-Nachweis · Aktuelle Neurologie
Gp120 induced neurotoxicity – The influence of the chemokine receptor tropism
DOI 10.1055/s-2006-953382
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR. Steinbach, M. Schreiber, H. Schaal, N. Haughey, A. Nath, G. Arendt, H. Köller
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Degeneration of neurons and astrocytes mediated by soluble viral proteins and neurotoxins is an important factor involved in the pathogenesis of HAD. We investigated whether different soluble HIV-1 envelope proteins (X4, R5 and R5X4 tropic HIV-1 gp120) induced apoptosis in neurons and astrocytes. Here we show that this effect is influenced by the structure and chemokine receptor tropism of the different gp120 isofor…
Zitieren
Zitierempfehlung
R. Steinbach, M. Schreiber, H. Schaal, N. Haughey, A. Nath, G. Arendt, H. Köller (2006) Gp120 induced neurotoxicity – The influence of the chemokine receptor tropism. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953382
Mit CareLit weiterarbeiten