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T-cell infiltration after chronic constriction injury of mouse sciatic nerve is associated with interleukin-17 expression and secondary macrophage recruitment

C. Kleinschnitz, H.H. Hofstetter, S.G. Meuth, S. Braeuninger, C. Sommer, G. Stoll · Aktuelle Neurologie · Ausgabe 09/2006

DOI 10.1055/s-2006-953411

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Autor:innenC. Kleinschnitz, H.H. Hofstetter, S.G. Meuth, S. Braeuninger, C. Sommer, G. Stoll
ZeitschriftAktuelle Neurologie
Ausgabe09/2006
Jahrgang / SeitenNicht angegeben

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Aims: Cytokine networks are involved in adaptive responses after peripheral nervous system injury. While it is well established that macrophages play a decisive role in nerve degeneration after chronic constriction injury (CCI) the role of T-cells is not yet well defined. Interleukin (IL)-17 is a novel proinflammatory cytokine produced by activated T-cells, but not macrophages. Objectives: In the present study, we i…

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Zitierempfehlung

C. Kleinschnitz, H.H. Hofstetter, S.G. Meuth, S. Braeuninger, C. Sommer, G. Stoll (2006) T-cell infiltration after chronic constriction injury of mouse sciatic nerve is associated with interleukin-17 expression and secondary macrophage recruitment. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2006-953411

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