CareLit · DOI-Nachweis · Zeitschrift für Phytotherapie
Screening Herbal Medicinal Products for CYP P450 enzyme inhibition with the fast, robust Supersome assay
DOI 10.1055/s-2006-954927
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Nachweis in CareLit
Autor:innenM Modarai, S Rahte, A Kortenkamp, M Heinrich
ZeitschriftZeitschrift für Phytotherapie
Ausgabe11/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The Supersome assay has long been used for industrial purposes to identify possible in vitro drug-drug interactions. Many of these interactions occur via induction or inhibition of the cytochrome P450 (CYP P450) enzyme system. The CYP P450 are a superfamily of membrane-bound, haeme-thiolate proteins, which are principally responsible for phase 1 oxidative metabolism and detoxification of xenobiotics and endobiotics…
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Zitierempfehlung
M Modarai, S Rahte, A Kortenkamp, M Heinrich (2006) Screening Herbal Medicinal Products for CYP P450 enzyme inhibition with the fast, robust Supersome assay. Zeitschrift für Phytotherapie (11). https://doi.org/10.1055/s-2006-954927
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