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The +1059G/C polymorphism in the CRP gene is associated with decreased serum CRP levels and involvement of the terminal ileum in patients with Crohn's disease

D Thalmaier, J Dambacher, J Seiderer, A Konrad, V Schachinger, S Pfennig, JM Otte, A Crispin, B Göke, T Ochsenkühn, P Lohse, S Brand · Zeitschrift für Gastroenterologie · Ausgabe 10/2006

DOI 10.1055/s-2006-955475

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Autor:innenD Thalmaier, J Dambacher, J Seiderer, A Konrad, V Schachinger, S Pfennig, JM Otte, A Crispin, B Göke, T Ochsenkühn, P Lohse, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe10/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background/Aims: Recently, a single nucleotide polymorphism in the CRP gene (1059G/C) has been reported. Our aim was to analyze the influence of this CRP polymorphism on the susceptibility and phenotype of Crohn's disease (CD). Methods: Using restriction fragment length polymorphism analysis, genomic DNA from 241 patients with CD and from 199 unrelated controls was analyzed for the +1059G/C substitution in the CRP g…

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D Thalmaier, J Dambacher, J Seiderer, A Konrad, V Schachinger, S Pfennig, JM Otte, A Crispin, B Göke, T Ochsenkühn, P Lohse, S Brand (2006) The +1059G/C polymorphism in the CRP gene is associated with decreased serum CRP levels and involvement of the terminal ileum in patients with Crohn's disease. Zeitschrift für Gastroenterologie (10). https://doi.org/10.1055/s-2006-955475

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