CareLit · DOI-Nachweis · Pneumologie
SNAI transcription factors in epithelial-to-mesenchymal transition: Comparative analysis of experimental and idiopathic pulmonary fibrosis
DOI 10.1055/s-2007-1032268
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Jayachandran, M Königshoff, H Yu, E Rupniewska, M Hecker, W Klepetko, W Seeger, O Eickelberg
ZeitschriftPneumologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by accumulation of activated (myo)fibroblasts and excessive extracellular matrix deposition, due to increased TGF-β signaling. TGF-β also induces epithelial-to-mesenchymal transition (EMT), the phenotypic switching of epithelial to fibroblast-like cells. EMT has recently been shown to occur in alveolar epithelial cells…
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Zitierempfehlung
A Jayachandran, M Königshoff, H Yu, E Rupniewska, M Hecker, W Klepetko, W Seeger, O Eickelberg (2008) SNAI transcription factors in epithelial-to-mesenchymal transition: Comparative analysis of experimental and idiopathic pulmonary fibrosis. Pneumologie (01). https://doi.org/10.1055/s-2007-1032268
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