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Surfactant alterations and lung fibrosis in a murine model of amiodarone-induced pulmonary fibrosis

P Mahavadi, L Schwertner, T Mokry, I Henneke, M Korfei, W Seeger, A Günther, C Ruppert · Pneumologie · Ausgabe 01/2008

DOI 10.1055/s-2007-1032270

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Autor:innenP Mahavadi, L Schwertner, T Mokry, I Henneke, M Korfei, W Seeger, A Günther, C Ruppert
ZeitschriftPneumologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben

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Introduction: Amiodarone (AD) belongs to the class III antiarrhythmic drugs, and prolongs phase 3 of the cardiac action potential. Because amiodarone has a low incidence of pro-arrhythmic effects, it is now widely used for acute and chronic treatment of (life-threatening) arrhythmias, but the use is limited by the pulmonary toxicity. Amiodarone may cause an acute pulmonary syndrome that appears just like typical pne…

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P Mahavadi, L Schwertner, T Mokry, I Henneke, M Korfei, W Seeger, A Günther, C Ruppert (2008) Surfactant alterations and lung fibrosis in a murine model of amiodarone-induced pulmonary fibrosis. Pneumologie (01). https://doi.org/10.1055/s-2007-1032270

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