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WISP1: A novel regulator of idiopathic pulmonary fibrosis amenable to therapeutic intervention

M Königshoff, A Jahn, K Kitowska, O Amarie, F Rose, L Fink, W Seeger, A Guenther, O Eickelberg · Pneumologie · Ausgabe 01/2008

DOI 10.1055/s-2007-1032272

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Autor:innenM Königshoff, A Jahn, K Kitowska, O Amarie, F Rose, L Fink, W Seeger, A Guenther, O Eickelberg
ZeitschriftPneumologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Idiopathic pulmonary fibrosis (IPF) is a devastating disease, characterized by severe loss of respiratory function due to enhanced extracellular matrix (ECM) deposition and (myo)fibroblast proliferation. Repetitive epithelial injuries with impaired alveolar wound healing represent a trigger mechanism for development of fibrosis, but molecular mechanisms linking alveolar epithelial cell (AEC) repair with development…

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Zitierempfehlung

M Königshoff, A Jahn, K Kitowska, O Amarie, F Rose, L Fink, W Seeger, A Guenther, O Eickelberg (2008) WISP1: A novel regulator of idiopathic pulmonary fibrosis amenable to therapeutic intervention. Pneumologie (01). https://doi.org/10.1055/s-2007-1032272

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