CareLit · DOI-Nachweis · Pneumologie
Phosphodiesterase 2 Inhibition diminished acute lung injury IN murine Pneumococcal Pneumonia
DOI 10.1055/s-2007-1032292
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Witzenrath, B Gutbier, B Schmeck, H Tenor, J Seybold, R Kuelzer, G Grentzmann, A Hatzelmann, TJ Mitchell, C Schudt, S Rosseau, N Suttorp, H Schütte
ZeitschriftPneumologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Severe pneumococcal pneumonia frequently causes respiratory failure. Both pathogen factors and an uncontrolled host response may contribute to acute lung injury (ALI) by impairing microvascular barrier function. Objectives: To analyze phosphodiesterase 2 (PDE2) as a potential target in pneumonia-induced lung microvascular hyperpermeability. Methods: HUVECs and isolated mouse lungs were challenged with the…
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Zitierempfehlung
M Witzenrath, B Gutbier, B Schmeck, H Tenor, J Seybold, R Kuelzer, G Grentzmann, A Hatzelmann, TJ Mitchell, C Schudt, S Rosseau, N Suttorp, H Schütte (2008) Phosphodiesterase 2 Inhibition diminished acute lung injury IN murine Pneumococcal Pneumonia. Pneumologie (01). https://doi.org/10.1055/s-2007-1032292
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