CareLit · DOI-Nachweis · Pneumologie
Lung-specific overexpression of CC chemokine ligand (CCL2) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis
DOI 10.1055/s-2007-1032293
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Autor:innenC Winter, K Taut, M Srivastava, F Länger, M Mack, DE Briles, JC Paton, R Maus, T Welte, MD Gunn, UA Maus
ZeitschriftPneumologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Mononuclear phagocytes are critical components of the lung innate host defense to inhaled bacterial pathogens. The monocyte chemotactic protein CCL2 plays a pivotal role in inflammatory mononuclear phagocyte recruitment. Here, we tested the hypothesis that increased CCL2-dependent mononuclear phagocyte recruitment would improve the lung innate host defense to infection with Streptococcus pneumoniae. Resu…
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Zitierempfehlung
C Winter, K Taut, M Srivastava, F Länger, M Mack, DE Briles, JC Paton, R Maus, T Welte, MD Gunn, UA Maus (2008) Lung-specific overexpression of CC chemokine ligand (CCL2) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis. Pneumologie (01). https://doi.org/10.1055/s-2007-1032293
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