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Macrophage turnover kinetics in the lungs of mice infected with Streptococcus pneumoniae

K Taut, C Winter, DE Briles, JC Paton, JW Christman, R Maus, R Baumann, T Welte, UA Maus · Pneumologie · Ausgabe 01/2008

DOI 10.1055/s-2007-1032294

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Autor:innenK Taut, C Winter, DE Briles, JC Paton, JW Christman, R Maus, R Baumann, T Welte, UA Maus
ZeitschriftPneumologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben

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Introduction: Streptococcus pneumoniae is the most prevalent cause of community-acquired pneumonia and is known to induce apoptosis and necrosis in macrophages in vivo. We analyzed the kinetics of alveolar and lung parenchymal macrophage replacement by newly recruited exudate macrophages in vehicle treated and S. pneumoniae challenged bone marrow chimeric CD45.1 mice. Methods: Following lethal irradiation, CD45.1 al…

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K Taut, C Winter, DE Briles, JC Paton, JW Christman, R Maus, R Baumann, T Welte, UA Maus (2008) Macrophage turnover kinetics in the lungs of mice infected with Streptococcus pneumoniae. Pneumologie (01). https://doi.org/10.1055/s-2007-1032294

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