CareLit · DOI-Nachweis · Pneumologie
Essential role of NFATc2 in CD8+ T cells in experimental model of asthma
DOI 10.1055/s-2007-967225
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Nachweis in CareLit
Autor:innenR Karwot, JH Maxeiner, S Schmitt, P Scholtes, K Sauer, M Hausding, A Doganci, HA Lehr, PR Galle, S Finotto
ZeitschriftPneumologie
Ausgabe02/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The present study demonstrates that mice lacking nuclear factor of activated T cells-2 (NFATc2) developed, in absence of allergen challenge, increased AHR, associated with lung hyperproliferating activated CD4+ Th2 as well as CD8 T cells defective in IFN-gamma production. Moreover, lung effector CD8+ T cells from NFATc2 (-/-) as well as CD8+ T cells from IFN-gamma (-/-) mice contained increased number of CD8+ CD122+…
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Zitierempfehlung
R Karwot, JH Maxeiner, S Schmitt, P Scholtes, K Sauer, M Hausding, A Doganci, HA Lehr, PR Galle, S Finotto (2007) Essential role of NFATc2 in CD8+ T cells in experimental model of asthma. Pneumologie (02). https://doi.org/10.1055/s-2007-967225
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