CareLit · DOI-Nachweis · Pneumologie
The Interleukin 13 Receptor System: A Novel Pathogenetic Mechanism in Pulmonary Arterial Hypertension
DOI 10.1055/s-2007-967239
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Hecker, G Kwapiszewska, A Zakrzewicz, L Marsh, U Seay, D Sedding, N Weissmann, W Klepetko, W Seeger, O Eickelberg
ZeitschriftPneumologie
Ausgabe02/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Interleukin (IL)-13 controls airway hyperresponsiveness and airway smooth muscle cell (SMC) hypertrophy, but its effect on pulmonary artery SMC has not been investigated thus far. Here, we examined the expression and activity of the IL-13 system in pulmonary arterial hypertension (PAH), including the receptor isotypes IL-4R, IL-13RA1, and IL-13RA2. Using quantitative RT-PCR, we detected increased expression of IL-13…
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Zitierempfehlung
M Hecker, G Kwapiszewska, A Zakrzewicz, L Marsh, U Seay, D Sedding, N Weissmann, W Klepetko, W Seeger, O Eickelberg (2007) The Interleukin 13 Receptor System: A Novel Pathogenetic Mechanism in Pulmonary Arterial Hypertension. Pneumologie (02). https://doi.org/10.1055/s-2007-967239
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