CareLit · DOI-Nachweis · Pneumologie
Snail and Slug are Key Mediators of TGF-beta-induced Epithelial-to-Mesenchymal Transition in Lung Fibrosis
DOI 10.1055/s-2007-967249
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Jayachandran, M Koenigshoff, M Hecker, H Yu, E Rupniewska, K Kitowska, W Seeger, O Eickelberg
ZeitschriftPneumologie
Ausgabe02/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by an increase of interstitial fibroblasts and excessive extracellular matrix deposition, in part mediated through enhanced TGF-β signaling. Epithelial-to-mesenchymal transition (EMT), the reversible phenotypic switching of epithelial to fibroblast-like cells, has recently been proposed as a causative factor in tissue fibrosis, but…
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Zitierempfehlung
A Jayachandran, M Koenigshoff, M Hecker, H Yu, E Rupniewska, K Kitowska, W Seeger, O Eickelberg (2007) Snail and Slug are Key Mediators of TGF-beta-induced Epithelial-to-Mesenchymal Transition in Lung Fibrosis. Pneumologie (02). https://doi.org/10.1055/s-2007-967249
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