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Defective lung CD8+ T cells lacking NFATc2 induced lung metastasis in NFATc2 deficient mice in a bronchoalveolar adenocarcinoma murine model

JH Maxeiner, R Karwot, K Sauer, P Scholtes, R Wiewrodt, PR Galle, HA Lehr, S Finotto · Pneumologie · Ausgabe 02/2007

DOI 10.1055/s-2007-967256

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Autor:innenJH Maxeiner, R Karwot, K Sauer, P Scholtes, R Wiewrodt, PR Galle, HA Lehr, S Finotto
ZeitschriftPneumologie
Ausgabe02/2007
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Lung cancer, including bronchoalveolar adenocarcinoma is the major cause of death in the USA and Europe. Although lung cancer has been unresponsive to the current immunotherapy, immune-responses to tumour were obtained by combined injection of bone marrow derived DCs and CTL inducing cytokines such as IL-7. IL-7 gene in fact was used because it has the capacity to stimulate CTL responses. The transcription factors n…

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Zitierempfehlung

JH Maxeiner, R Karwot, K Sauer, P Scholtes, R Wiewrodt, PR Galle, HA Lehr, S Finotto (2007) Defective lung CD8+ T cells lacking NFATc2 induced lung metastasis in NFATc2 deficient mice in a bronchoalveolar adenocarcinoma murine model. Pneumologie (02). https://doi.org/10.1055/s-2007-967256

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