CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Increased CTGF expression occurs in human and mouse hepatocytes of damaged livers and is mediated by TGF-β signaling
DOI 10.1055/s-2007-967757
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Nachweis in CareLit
Autor:innenH Weng, H Gaitantzi, L Ciuclan, Y Liu, E Ueberham, R Gebhardt, S Kanzler, R Heuchel, K Breitkopf, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Connective Tissue Growth Factor (CTGF) is an important mediator of profibrogenic TGF-β actions in liver. Hepatic stellate cells and bile duct epithelial cells were recognized as its cellular source in liver. Here, we demonstrate CTGF expression in hepatocytes in vitro and in vivo and identify TGF-β as inducer of CTGF. Primary cultured hepatocytes were stimulated with TGF-β. Real-Time PCR and Western blot analyses we…
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Zitierempfehlung
H Weng, H Gaitantzi, L Ciuclan, Y Liu, E Ueberham, R Gebhardt, S Kanzler, R Heuchel, K Breitkopf, S Dooley (2007) Increased CTGF expression occurs in human and mouse hepatocytes of damaged livers and is mediated by TGF-β signaling. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967757
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