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Expression profile and functional activity of Platelet-derived growth factor-C and -D in bile duct-ligated rat livers and transdifferentiating hepatic stellate cells

E Borkham-Kamphorst, AM Gressner, R Weiskirchen · Zeitschrift für Gastroenterologie · Ausgabe 01/2007

DOI 10.1055/s-2007-967759

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Autor:innenE Borkham-Kamphorst, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben

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Background/Aims: We analyzed the expression of the novel identified platelet-derived growth factor-C and -D (PDGF-C, PDGF-D) in an experimental bile duct-ligated rat model and compared them to those of PDGF-A, PDGF-B and their receptors, and assessed the biological function of these novel cytokines in cultured hepatic stellate cells (HSC). Methods: The mRNA for PDGF-A, -B, -C, and –D, as well as for PDGF receptor-α…

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E Borkham-Kamphorst, AM Gressner, R Weiskirchen (2007) Expression profile and functional activity of Platelet-derived growth factor-C and -D in bile duct-ligated rat livers and transdifferentiating hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967759

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