CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGF-β interference with MEOS and ADH metabolising systems may promote alcohol dependent liver damage
DOI 10.1055/s-2007-967764
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Autor:innenL Ciuclan, P Godoy, S Ehnert, H Weng, MV Singer, K Breitkopf, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Fibrogenesis involves cytokines, acetaldehyde, oxidative stress and complex interactions between liver cells. Hepatotoxic effects of chronic alcohol comsumption result from activating ADH and MEOS systems. TGF-β is induced in liver of patients with alcoholic liver disease, suggesting its involvement adverse effects of alcohol, however, a molecular connection was not yet identified. Aim: To show a crosstalk bet…
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Zitierempfehlung
L Ciuclan, P Godoy, S Ehnert, H Weng, MV Singer, K Breitkopf, S Dooley (2007) TGF-β interference with MEOS and ADH metabolising systems may promote alcohol dependent liver damage. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967764
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