CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The knockout of latent transforming growth factor-β binding protein–1 (LTBP–1) affects the fibrogenic potential in mice liver
DOI 10.1055/s-2007-967765
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Autor:innenF Drews, S Knöbel, A Bosio, C Conrad, M Moser, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Latent transforming growth factor-β binding proteins (LTBP–1, –2, 3-, –4) are glycosylated proteins of the extracellular matrix involved in the secretion and controlling the bioavailability of active transforming growth factor-β (TGF-β). LTBP–1 and TGF-β are key factors in the pathophysiology of liver fibrogenesis. During this process, hepatic stellate cells (HSC) become activated and transdifferentiate into m…
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Zitierempfehlung
F Drews, S Knöbel, A Bosio, C Conrad, M Moser, AM Gressner, R Weiskirchen (2007) The knockout of latent transforming growth factor-β binding protein–1 (LTBP–1) affects the fibrogenic potential in mice liver. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967765
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