CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Bone morphogenetic protein–7 (BMP–7), a neglected player in hepatic fibrosis?
DOI 10.1055/s-2007-967780
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Autor:innenOA Scherner, SK Meurer, R Weiskirchen, AM Gressner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: BMP–7 is a member of the TGF-β superfamily, that has been shown to counteract the profibrogenic signaling of TGF-β [1] The supplementation of exogenous recombinant BMP–7 suppresses experimental renal fibrosis [2]. In vitro BMP–7 antagonizes TGF-β1-induced epithelial-to-mesenchymal transition. The expression and putative function of BMP–7 in the process of liver fibrosis, however, has not been analyzed so fa…
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Zitierempfehlung
OA Scherner, SK Meurer, R Weiskirchen, AM Gressner (2007) Bone morphogenetic protein–7 (BMP–7), a neglected player in hepatic fibrosis?. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967780
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