CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Blockade of the sympathicus by inhibition of beta-adrenoreceptors results in delayed fibrosis in MDR2 knockout mice
DOI 10.1055/s-2007-967784
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Nachweis in CareLit
Autor:innenI Strack, M Scheffler, K Petmecky, S Schulte, F Lammert, O Dirsch, HP Dienes, M Odenthal
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Transdifferentiation of hepatic stellate cells (HSC) into myofibroblastic cells is one of the central mechanisms of liver fibrogenesis. Activated myofibroblastic cells are the main producers of extracellular matrix. Recent reports have shown that HSC express neurotrophic mediators after myofibroblastic activation and that blockade of the sympathetic signalling reduces the fibrogenic activity of HSC in vitro and in e…
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Zitierempfehlung
I Strack, M Scheffler, K Petmecky, S Schulte, F Lammert, O Dirsch, HP Dienes, M Odenthal (2007) Blockade of the sympathicus by inhibition of beta-adrenoreceptors results in delayed fibrosis in MDR2 knockout mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967784
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