CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cell type-specific effects on CTGF and PAI–1 expression when glucocorticoids meet TGF-β in primary liver cells
DOI 10.1055/s-2007-967790
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Wickert, N Chatain, K Kruschinsky, AM Gressner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Glucocorticoids are involved in fundamental cellular functions such as glucose metabolism and cell differentiation. Once bound to their receptor (GR) the glucocorticoid-receptor-complex translocates to the nucleus and binds after dimerization to a cis-active response element in order to regulate target genes. A pivotal process in liver fibrosis is the activation of hepatic stellate cells (HSC) and the producti…
Zitieren
Zitierempfehlung
L Wickert, N Chatain, K Kruschinsky, AM Gressner (2007) Cell type-specific effects on CTGF and PAI–1 expression when glucocorticoids meet TGF-β in primary liver cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967790
Mit CareLit weiterarbeiten