CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Glucosylcerebrosid accumulation in liver of bile acid beta glucosidase (Gba2) knockout mouse
DOI 10.1055/s-2007-967793
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Autor:innenY Yildiz, H Matern, S Matern, T Sauerbruch, F Lammert, DW Russell
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
A novel microsomal bile acid beta glucosidase (GBA2) has been purified and characterized from human liver. The bile acid beta glucosidase hydrolyzes specifically bile acid 3-O-glucosides as endogenous compounds in liver. However, GBA2 is highly expressed in many tissues, including liver, brain, testes, bone marrow, and muscle. Since some of these tissues are not involved in bile acid metabolism, a Gba2 knockout (Gba…
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Zitierempfehlung
Y Yildiz, H Matern, S Matern, T Sauerbruch, F Lammert, DW Russell (2007) Glucosylcerebrosid accumulation in liver of bile acid beta glucosidase (Gba2) knockout mouse. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967793
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