CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The MODY2 gene glucokinase is negatively regulated by FoxO forkhead transcription factors
DOI 10.1055/s-2007-967806
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Autor:innenG Ganjam, T Kietzmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Glucokinase (GK) plays a key role in the regulation of glucose utilization in hepatocytes. Defects in the glucokinase gene have been linked to maturity-onset diabetes of the young (non-insulin-dependent, also called MODY–2) permanent neonatal diabetes (PNDM) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). Insulin is a major regulator of GK expression, however, the knowledge of the involved transcript…
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Zitierempfehlung
G Ganjam, T Kietzmann (2007) The MODY2 gene glucokinase is negatively regulated by FoxO forkhead transcription factors. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967806
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