CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
IFN-gamma prevents chemically induced hepatocellular carcinoma and preneoplastic lesions in liver independent of functional T-cells
DOI 10.1055/s-2007-967815
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Autor:innenS Lüth, J Andreas, P Schirmacher, K Reifenberg, M Schuchmann, J Herkel, AW Lohse
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Transgenic mice, which overexpress IFN-gamma in the liver, suffer from chronic hepatitis. Chronic hepatitis is believed to promote hepatocarcinogenesis. To test whether IFN-gamma transgenic mice are more suscepitible for the development of liver cancer, we chemically induced hepatocarcinogenesis in IFN-gamma transgenic or non-transgenic mice by treatment with diethylnitrosamine (DEN), promoted by Phenobarbital (PB)…
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Zitierempfehlung
S Lüth, J Andreas, P Schirmacher, K Reifenberg, M Schuchmann, J Herkel, AW Lohse (2007) IFN-gamma prevents chemically induced hepatocellular carcinoma and preneoplastic lesions in liver independent of functional T-cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967815
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