CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The dual EGF-/VEGF-receptor tyrosine kinase inhibitor AEE–788 inhibits growth of human hepatocellular carcinoma xenografts in mice
DOI 10.1055/s-2007-967821
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Nachweis in CareLit
Autor:innenM Ocker, K Okamoto, D Neureiter, B Kaufmann, U Haus, C Herold
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Treatment for advanced stages of hepatocellular carcinoma (HCC) remains unsatisfactory. HCC is a highly vascularised tumor and also shows enhanced expression of epidermal growth factor receptors. We therefore investigated the effect of AEE–788, a novel inhibitor of the receptor tyrosine kinase activity of the EGF and the VEGF receptor, for HCC treatment in vitro and in a subcutaneous xenograft model in vivo. M…
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Zitierempfehlung
M Ocker, K Okamoto, D Neureiter, B Kaufmann, U Haus, C Herold (2007) The dual EGF-/VEGF-receptor tyrosine kinase inhibitor AEE–788 inhibits growth of human hepatocellular carcinoma xenografts in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967821
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