CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Telomere shortening and p21-checkpoint inactivation characterize multistep hepatocarcinogenesis in humans
DOI 10.1055/s-2007-967822
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Autor:innenRR Plentz, A Lechel, YN Park, H Kim, F Nellessen, BHE Langkopf, L Wilkens, MP Manns, A Destro, B Fiamengo, M Roncalli, KL Rudolph
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Telomere shortening and DNA-damage-checkpoint inactivation have been identified as molecular hallmarks characterizing early carcinogenesis in humans but it is unknown, whether these molecular features coincide at specific stages of multistep carcinogenesis in humans. The preneoplasia-carcinoma sequence of human hepatocellular carcinoma (HCC) is not well defined. Small cell changes (SCC) and large cell changes (LCC)…
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Zitierempfehlung
RR Plentz, A Lechel, YN Park, H Kim, F Nellessen, BHE Langkopf, L Wilkens, MP Manns, A Destro, B Fiamengo, M Roncalli, KL Rudolph (2007) Telomere shortening and p21-checkpoint inactivation characterize multistep hepatocarcinogenesis in humans. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967822
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