CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Maintained expression of alternative bile salt excretion pathways in inflammatory cholestasis in mice by treatment with class II nuclear hormon receptor ligands
DOI 10.1055/s-2007-967834
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Voigt, IV Martin, M Trauner, CG Dietrich, C Gartung, C Trautwein, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Expression of hepatic organic anion transporters including basolateral overflow systems such as Mrp3 and Mrp4 is decreased during inflammatory cholestasis by experimental treatment with endotoxin (LPS). This crucial event putatively occurs by a cytokine-induced nucleocytoplasmic shift of RXR, the obligate heterodimerization partner of transactivating class II nuclear hormon receptors (NHR), as a central mechan…
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Zitierempfehlung
S Voigt, IV Martin, M Trauner, CG Dietrich, C Gartung, C Trautwein, A Geier (2007) Maintained expression of alternative bile salt excretion pathways in inflammatory cholestasis in mice by treatment with class II nuclear hormon receptor ligands. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967834
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