CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Sensitization of hepatocytes by methyltransferase-inhibitor 5-azacytidine against cytokine-mediated cell death
DOI 10.1055/s-2007-967887
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Nachweis in CareLit
Autor:innenT Weiland, A Wendel, G Künstle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background 5-Azacytidine (5-aza-CR) was developed as an antineoplastic agent long before its inhibitory activity on DNA methyltransferases and thus its ability to reverse aberrant gene silencing became evident. Today, 5-aza-CR is the first DNA hypomethylating agent approved for treatment of myelodysplastic syndromes and represents a promising drug for epigenetic cancer therapy. However, 5-aza-CR is contraindicated f…
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Zitierempfehlung
T Weiland, A Wendel, G Künstle (2007) Sensitization of hepatocytes by methyltransferase-inhibitor 5-azacytidine against cytokine-mediated cell death. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2007-967887
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