The Story of Inhaled Insulin

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Introduction The feasibility of inhaled insulin was demonstrated in diabetics in Germany in 1925 (1). But the efficiency was low (˜3%) and at the time, insulin was in very short supply. This early observation was forgotten and the feasibility of inhaled insulin was again demonstrated in humans in l971, but it was uncertain if the correct dose could be reliably given (2). Then in the 1980s a series of nebulization st…

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