CareLit · DOI-Nachweis · Endoskopie heute
Characterization and predictive value of epidermal growth factor receptor using semi-quantitative real time PCR after deparafinization in comparison to immunohistochemistry on colorectal cancer specimens
DOI 10.1055/s-2007-974204
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Nachweis in CareLit
Autor:innenA. Hoffman, A. Müller, M. Möhler, P.R. Galle
ZeitschriftEndoskopie heute
Ausgabe03/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Epidermal growth factor receptor (EGFR) is overexpressed in many types of cancers, especially colorectal cancers, and seems to reflect more aggressive histological and clinical course. Cetuximab is a chimeric murin-human monoclonal antibody that targets the extracellular domain of the EGFR. Immunohistochemstry (IHC) has by far been the most commonly used method, with almost all clinical cetuximab trial…
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Zitierempfehlung
A. Hoffman, A. Müller, M. Möhler, P.R. Galle (2007) Characterization and predictive value of epidermal growth factor receptor using semi-quantitative real time PCR after deparafinization in comparison to immunohistochemistry on colorectal cancer specimens. Endoskopie heute (03). https://doi.org/10.1055/s-2007-974204
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