CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
FoxO1 ablation in hypothalamic pomc neurons reduces food intake and body weight
DOI 10.1055/s-2007-982140
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Autor:innenL Plum, M Matsumoto, D Accili
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Insulin and leptin control food intake in part by regulating the transcription of orectic and anorectic neuropeptides in the hypothalamus. Activation of insulin receptor signaling results in nuclear exclusion of the transcription factor forkhead box-containing protein of the O subfamily (FoxO)-1, while Leptin activates the signal transducer and activator of transcription 3 (Stat3). We have previously shown that FoxO…
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Zitierempfehlung
L Plum, M Matsumoto, D Accili (2007) FoxO1 ablation in hypothalamic pomc neurons reduces food intake and body weight. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982140
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