CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Inhibition of human proinsulin promoter activity by Krueppel-like transcription factor 11 (KLF11) is mediated through functional interactions with PDX-1 and a proximal CACCC box
DOI 10.1055/s-2007-982144
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Nachweis in CareLit
Autor:innenG Päth, X Niu, N Perakakis, K Laubner, C Limbert, T Stahl, J Seufert
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Krueppel-like transcription factor 11 (KLF11, TIEG2) is a member of the Sp1/KLF transcription factor family which plays an important role in mammalian gene regulation via binding to GC-rich promoter elements comprising CGCCC (GC) or CACCC box core sequences. Previously we demonstrated that human KLF11 (hKLF11) inhibits human proinsulin promoter activity in rodent beta-cell lines (INS-1, beta-TC3). At ins…
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Zitierempfehlung
G Päth, X Niu, N Perakakis, K Laubner, C Limbert, T Stahl, J Seufert (2007) Inhibition of human proinsulin promoter activity by Krueppel-like transcription factor 11 (KLF11) is mediated through functional interactions with PDX-1 and a proximal CACCC box. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982144
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