CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
RX871024 but not Efaroxan stimulates insulin secretion by a KATP independent mechanism
DOI 10.1055/s-2007-982145
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Autor:innenM Willenborg, A Wienbergen, L Aguilar-Bryan, J Bryan, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Within a certain concentration range the first generation imidazoline, RX871024, enhances insulin release only when the glucose concentration by itself is stimulatory (glucose-selectivity). This effect was ascribed to the activation of a KATP channel-independent pathway in addition to the direct closure of KATP-channels. Here we show that efaroxan, another glucose-selective, first generation imidazolin…
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Zitierempfehlung
M Willenborg, A Wienbergen, L Aguilar-Bryan, J Bryan, I Rustenbeck (2007) RX871024 but not Efaroxan stimulates insulin secretion by a KATP independent mechanism. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982145
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