CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
The high expression of microRNAs in brain of BB rats may act as a central switchbox of the beta-cell destruction
DOI 10.1055/s-2007-982166
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Nachweis in CareLit
Autor:innenP Lutze, R Baguhl, I Klöting
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aim: To prove the relevance of diabetogenic gene, Iddm4, mapped on rat chromosome 6q32, a segment of the SHR chromosome 6 (D6Rat66-D6Rat3) was introgressed into the BB/OK background termed briefly BB.6S. These congenic BB.6S rats showed a dramatic reduction of diabetes frequency compared with BB/OK (14 vs. 89%). The generation of subcogenic BB.6S rats, their phenotypic characterisation and comparative gene expressio…
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Zitierempfehlung
P Lutze, R Baguhl, I Klöting (2007) The high expression of microRNAs in brain of BB rats may act as a central switchbox of the beta-cell destruction. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982166
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