CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Lentiviral short hairpin ribonucleic acid-mediated knockdown of Akt isoforms in human adipocytes
DOI 10.1055/s-2007-982232
Bibliografische Angaben
Nachweis in CareLit
Autor:innenP Fischer-Posovszky, A Killian, KM Debatin, M Wabitsch
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objectives: Obesity is associated with severe co-morbidities such as insulin resistance and type 2 diabetes. In some animal models, insulin resistance is associated with an increased rate of fat cell apoptosis. Here, we have generated human insulin resistant adipocytes at the level of Akt using a lentiviral RNAi system in order to study whether insulin resistance interferes with apoptosis sensitivity in human adipoc…
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Zitierempfehlung
P Fischer-Posovszky, A Killian, KM Debatin, M Wabitsch (2007) Lentiviral short hairpin ribonucleic acid-mediated knockdown of Akt isoforms in human adipocytes. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982232
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